Genome homology of vesicular stomatitis virus and defective T particles and evidence for the sequential transcription of the virion ribonucleic acid
- PMID: 4338640
- PMCID: PMC356400
- DOI: 10.1128/JVI.9.6.946-955.1972
Genome homology of vesicular stomatitis virus and defective T particles and evidence for the sequential transcription of the virion ribonucleic acid
Abstract
The small defective T particle of vesicular stomatitis virus (VSV-111) has no detectable enzyme activity when assayed at 31 C, although qualitatively it possesses all the virion proteins found in complete VSV-1 virions. With VSV-1 transcription product ribonucleic acid (RNA), it is shown that the VSV-111 RNA is identical to part of the VSV-1 genome. Evidence is also presented to support the idea that in vitro VSV-1 transcription is sequential.
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