A micrometabolic inhibition test for the estimation of poliovirus neutralizing antibodies
- PMID: 4345395
- PMCID: PMC2480891
A micrometabolic inhibition test for the estimation of poliovirus neutralizing antibodies
Abstract
A modified micrometabolic inhibition test for the titration of poliovirus neutralizing antibodies is described. The effects of varying both the duration and the temperature of incubation of the serum-virus mixtures were examined. Overnight incubation resulted in a 2-3-fold increase in the titre of the hyperimmune sera tested. The method is simple and economical and appears to be suitable for antibody surveys.
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