Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1972 Dec;10(6):1091-7.
doi: 10.1128/JVI.10.6.1091-1097.1972.

Transient inhibition of polyoma virus synthesis by Sendai virus (parainfluenza I). I. Demonstration and nature of the inhibition by inactivated virus

G L Smith, R A Consigli

Transient inhibition of polyoma virus synthesis by Sendai virus (parainfluenza I). I. Demonstration and nature of the inhibition by inactivated virus

G L Smith et al. J Virol. 1972 Dec.

Abstract

Superinfection of polyoma virus-infected mouse embryo cells by beta-propiolactone-inactivated Sendai virus resulted in a 90% inhibition of the synthesis of infectious polyoma progeny. The interference is dependent upon the time of superinfection and the concentration of the inactivated virus. The inhibition of polyoma virus synthesis is transient in nature since normal synthesis of polyoma progeny virus is seen upon prolonged incubation. Interferon does not appear to be implicated in the interference. Various aspects of the biological and synthetic capabilities of beta-propiolactone-inactivated Sendai virus are also described.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Virol. 1968 Oct;2(10):1028-37 - PubMed
    1. Proc Natl Acad Sci U S A. 1965 Dec;54(6):1579-84 - PubMed
    1. Proc Natl Acad Sci U S A. 1967 Jul;58(1):127-33 - PubMed
    1. Science. 1971 Jan 8;171(3966):75-7 - PubMed
    1. Proc Soc Exp Biol Med. 1965 Nov;120(2):533-8 - PubMed

MeSH terms

LinkOut - more resources