Adenosine 3':5'-cyclic monophosphate as a regulator of bacterial transformation
- PMID: 4346890
- PMCID: PMC433285
- DOI: 10.1073/pnas.70.2.471
Adenosine 3':5'-cyclic monophosphate as a regulator of bacterial transformation
Abstract
Adenosine 3':5'-cyclic monophosphate added to exponentially growing cells of Hemophilus influenzae strain Rd increases competence for transformation 100- to 10,000-fold. Cyclic AMP added to near-stationary or stationary cells does not increase competence over the high level normally found in the early stationary phase.
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