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. 1973 Feb;11(2):232-7.
doi: 10.1128/JVI.11.2.232-237.1973.

Effect of viral double-stranded RNA on protein synthesis in intact cells

B Cordell-Stewart, M W Taylor

Effect of viral double-stranded RNA on protein synthesis in intact cells

B Cordell-Stewart et al. J Virol. 1973 Feb.

Abstract

The addition of purified, noninfectious, double-stranded RNA of bovine enterovirus, a picornavirus, to intact cells in culture results in a rapid cessation of cellular polypeptide synthesis. This inhibition is specific for host cell protein synthesis since the translation of picornavirus-specific proteins is not affected by the double-stranded viral RNA.

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References

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