doi: 10.1007/BF00504758.
Increase by alpha-adrenolytic drugs of acetylcholine release evoked by field stimulation of the guinea-pig ileum
- PMID: 43477
- DOI: 10.1007/BF00504758
Item in Clipboard
Increase by alpha-adrenolytic drugs of acetylcholine release evoked by field stimulation of the guinea-pig ileum
Naunyn Schmiedebergs Arch Pharmacol.
1979 Nov.
Abstract
The release of acetylcholine evoked by field stimulation of the guinea-pig ileum (3 Hz) is increased by yohimbine and tolazoline but not affected by phentolamine. It is proposed that yohimbine and tolazoline by blocking alpha-adrenoceptors of the cholinergic nerves abolish the inhibition caused by endogenous noradrenaline, and thus facilitate the output of acetylcholine.
Similar articles
-
Distribution and types of adrenoceptors in the guinea-pig ileum: the action of alpha- and beta-adrenoceptor blocking agents.Br J Pharmacol. 1982 Aug;76(4):569-78. doi: 10.1111/j.1476-5381.1982.tb09256.x. Br J Pharmacol. 1982. PMID: 6125224 Free PMC article.
-
The effects of prazosin, phentolamine and phenoxybenzamine on inhibitory alpha-adrenoceptors in the guniea-pig isolated ileum.Br J Pharmacol. 1982 Jun;76(2):235-43. doi: 10.1111/j.1476-5381.1982.tb09212.x. Br J Pharmacol. 1982. PMID: 6284289 Free PMC article.
-
Homogeneous and non-homogeneous distribution of inhibitory and excitatory adrenoceptors in the longitudinal muscle of the guinea-pig ileum.Br J Pharmacol. 1982 Aug;76(4):603-11. doi: 10.1111/j.1476-5381.1982.tb09260.x. Br J Pharmacol. 1982. PMID: 7104527 Free PMC article.
-
The effects of metoclopramide on acetylcholine release and on smooth muscle response in the isolated guinea-pig ileum.Naunyn Schmiedebergs Arch Pharmacol. 1982 Jun;319(3):231-8. doi: 10.1007/BF00495871. Naunyn Schmiedebergs Arch Pharmacol. 1982. PMID: 7110382
-
Mechanisms of facilitation and muscarinic or alpha-adrenergic inhibition of acetylcholine and noradrenaline secretion from peripheral nerves.Acta Physiol Scand Suppl. 1982;506:1-39. Acta Physiol Scand Suppl. 1982. PMID: 6293252 Review.
Cited by
-
A submucosal mechanism for catecholamine-induced increases in fluid absorption in rabbit ileum in vitro.J Physiol. 1988 Oct;404:385-405. doi: 10.1113/jphysiol.1988.sp017295. J Physiol. 1988. PMID: 3150986 Free PMC article.
-
Presynaptic effects of scopolamine, oxotremorine, noradrenaline and morphine on [3H]acetylcholine release from the myenteric plexus at different stimulation frequencies and calcium concentrations.Naunyn Schmiedebergs Arch Pharmacol. 1987 Jun;335(6):597-604. doi: 10.1007/BF00166974. Naunyn Schmiedebergs Arch Pharmacol. 1987. PMID: 2819741
-
Alpha- and beta-adrenoceptor-mediated responses of the guinea-pig ileum and the effects of neuronal uptake inhibition.Naunyn Schmiedebergs Arch Pharmacol. 1985 Dec;331(4):316-23. doi: 10.1007/BF00500813. Naunyn Schmiedebergs Arch Pharmacol. 1985. PMID: 2869413
-
Effect of alpha-adrenoceptor agonists and antagonists on cholinergic transmission in guinea-pig isolated atria.Naunyn Schmiedebergs Arch Pharmacol. 1986 Sep;334(1):40-7. doi: 10.1007/BF00498738. Naunyn Schmiedebergs Arch Pharmacol. 1986. PMID: 2878372
-
Impulse interval-dependent effect of sympathetic nerve stimulation on evoked acetylcholine release from the rabbit perfused atria preparation.Naunyn Schmiedebergs Arch Pharmacol. 1995 Feb;351(2):156-63. doi: 10.1007/BF00169329. Naunyn Schmiedebergs Arch Pharmacol. 1995. PMID: 7770097