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. 1979 Nov;309(3):255-7.
doi: 10.1007/BF00504758.

Increase by alpha-adrenolytic drugs of acetylcholine release evoked by field stimulation of the guinea-pig ileum

H Kilbinger, I Wessler

Increase by alpha-adrenolytic drugs of acetylcholine release evoked by field stimulation of the guinea-pig ileum

H Kilbinger et al. Naunyn Schmiedebergs Arch Pharmacol. 1979 Nov.

Abstract

The release of acetylcholine evoked by field stimulation of the guinea-pig ileum (3 Hz) is increased by yohimbine and tolazoline but not affected by phentolamine. It is proposed that yohimbine and tolazoline by blocking alpha-adrenoceptors of the cholinergic nerves abolish the inhibition caused by endogenous noradrenaline, and thus facilitate the output of acetylcholine.

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