Time of enterotoxin formation and release during sporulation of Clostridium perfringens type A
- PMID: 4347930
- PMCID: PMC285311
- DOI: 10.1128/jb.113.2.932-936.1973
Time of enterotoxin formation and release during sporulation of Clostridium perfringens type A
Abstract
Clostridium perfringens enterotoxin was detected intracellularly about 3 hr after the inoculation of vegetative cells into sporulation medium. The subsequent increase in intracellular enterotoxin concentration roughly paralleled but followed by 2.5 to 5 hr the increase in number of heat-resistant spores. The increase in biologically active toxin coincided with the increase in enterotoxin antigen. Enterotoxin was released from the sporangium with its lysis, concomitantly with the mature spore release.
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