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. 1979 Feb;54(2):123-6.
doi: 10.1136/adc.54.2.123.

Reduction of insulin dose on changing diabetic children from standard to monocomponent insulins

N K Griffin, M A Smith, J D Baum

Reduction of insulin dose on changing diabetic children from standard to monocomponent insulins

N K Griffin et al. Arch Dis Child. 1979 Feb.

Abstract

21 diabetic children requiring greater than 50 units of standard insulin daily were changed to a monocomponent insulin. During the 3 months before the change the insulin dose had risen significantly from a mean of 70 to a mean of 77 units daily. During the 3 months after the change the dose fell significantly to a mean of 53 units daily. This decrease in insulin requirement was associated with a general improvement in diabetic control. This was assessed clinically and measured in 10 children by an analysis of home urine tests and in 8 children by an analysis of 24-hour urine glucose excretion.

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