Anemone toxin discriminates between ionic channels for receptor potential and for action potential production in a sensory neuron
- PMID: 43492
- DOI: 10.1016/0304-3940(79)91512-x
Anemone toxin discriminates between ionic channels for receptor potential and for action potential production in a sensory neuron
Abstract
The effect of anemone toxin (ATX II), which slows sodium channel inactivation at electrically excitable membranes, was investigated in the slowly adapting stretch receptor organ of crayfish. The toxin affected the action potentials, but produced no changes in the stretch induced receptor potentials. This finding is further proof for the high selectivity of this toxin molecule for sodium channels which are gated by membrane depolarissations.
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