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. 1973 Apr;11(4):487-501.
doi: 10.1128/JVI.11.4.487-501.1973.

Initiation and direction of RNA transcription by vesicular stomatitis virus virion transcriptase

P Roy, D H Bishop

Initiation and direction of RNA transcription by vesicular stomatitis virus virion transcriptase

P Roy et al. J Virol. 1973 Apr.

Abstract

The initiation of RNA transcription by the virion-bound RNA transcriptase of vesicular stomatitis virus has been examined. Multiple initiation sequences have been observed, two of which have been characterized (pppApCpGp... and pppGpCp...) suggestive of a transcription process which can start at different sites along the template RNA. By the use of sequential labeling techniques and exonucleases, it has been determined that there is a 5' to 3' direction of product RNA synthesis.

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References

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