Glia-induced morphological differentiation in neuroblastoma cells
- PMID: 4352661
- PMCID: PMC433621
- DOI: 10.1073/pnas.70.6.1894
Glia-induced morphological differentiation in neuroblastoma cells
Abstract
Glial cells release a factor into their culture medium that induces a high degree of morphological differentiation in neuroblastoma cells under normal growth conditions. This phenomenon is not correlated with a change in intracellular adenosine 3':5'-cyclic monophosphate or in the rate of cell growth. Media from other cell lines tested induce less morphological differentiation or have no effect.
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