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. 1973 Aug 11;3(5875):323-5.
doi: 10.1136/bmj.3.5875.323.

Smooth muscle autoantibodies in infectious mononucleosis

E J Holborow, E H Hemsted, S V Mead

Smooth muscle autoantibodies in infectious mononucleosis

E J Holborow et al. Br Med J. .

Abstract

Smooth muscle antibodies (S.M.A.) were found in the sera of 81% of 126 patients over 10 years old with seropositive infectious mononucleosis tested within one month of onset. In 27 patients presenting clinically with infectious mononucleosis but having negative Paul-Bunnell tests the incidence of S.M.A. was 44%. In children 10 years of age or less in these two categories S.M.A. were present in 75% and 25% respectively, while in children of similar age not suspected of having infectious mononucleosis the incidence of S.M.A. was 10%. Among 45 adults with past histories of seropositive infectious mononucleosis more than one year before the incidence of S.M.A. was 33%, in contrast to 14% in 98 subjects with a negative history for infectious mononucleosis.

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