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. 1979 May 1;584(2):358-62.
doi: 10.1016/0304-4165(79)90282-4.

Increase in liver acid lipase of thyroidectomized rats by thyroid hormones and its inhibition by actinomycin D

P M Coates, H Lau, L Krulich, S A Brown, O Koldovsky

Increase in liver acid lipase of thyroidectomized rats by thyroid hormones and its inhibition by actinomycin D

P M Coates et al. Biochim Biophys Acta. .

Abstract

Acid lipase activity in the livers of thyroidectomized rats is increased by administration of L-thyroxine. The response is dose-dependent and can be demonstrated within 12 h after treatment. L-Triiodothyronine also evokes a rapid increase in acid lipase activity, and this increase can be inhibited by coadministration of actinomycin D.

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