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. 1973 Dec;70(12):3566-70.
doi: 10.1073/pnas.70.12.3566.

In vitro synthesis of RNA that contains polyadenylate by virion-associated RNA polymerase of vesicular stomatitis virus

A K Banerjee, D P Rhodes

In vitro synthesis of RNA that contains polyadenylate by virion-associated RNA polymerase of vesicular stomatitis virus

A K Banerjee et al. Proc Natl Acad Sci U S A. 1973 Dec.

Abstract

The RNA synthesized in vitro by the virion-associated RNA-instructed RNA polymerase of purified vesicular stomatitis virus contains polyadenylate sequences. These have been demonstrated by their partial resistance to pancreatic and T(1) ribonucleases and their capacity to bind to poly(U) filters and oligo(dT)-cellulose. The polyadenylate sequences range in apparent size from 50 to 200 bases, similar to the size of the poly(A) in mRNA from vesicular stomatitis virus-infected cells. Possible mechanisms of polyadenylylation of the in vitro RNA product are discussed.

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References

    1. Virology. 1966 Oct;30(2):161-72 - PubMed
    1. Bull Soc Chim Biol (Paris). 1966;48(10):1037-75 - PubMed
    1. J Mol Biol. 1966 Dec 28;22(2):381-4 - PubMed
    1. Proc Natl Acad Sci U S A. 1970 Jun;66(2):572-6 - PubMed
    1. J Virol. 1970 Jul;6(1):1-11 - PubMed

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