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Comparative Study
. 1974 Jan;13(1):181-5.
doi: 10.1128/JVI.13.1.181-185.1974.

Endogenous C-type viruses of BALB-c cells: frequencies of spontaneous and chemical induction

S A Aaronson, C Y Dunn
Comparative Study

Endogenous C-type viruses of BALB-c cells: frequencies of spontaneous and chemical induction

S A Aaronson et al. J Virol. 1974 Jan.

Abstract

A sensitive biological assay has been developed for studying the frequency of virus induction from mouse cells containing poorly infectious endogenous C-type viruses. A low spontaneous frequency of virus activation of one but not a second endogenous virus of BALB/c cells has been demonstrated. The resistance of BALB/c cells to superinfection by the more inducible virus appears to be absolute, whereas resistance to the other virus is only relative. Thus, the evidence indicates that the BALB/c cell exerts differential effects at two levels of regulation on the expression of its biologically distinguishable endogenous C-type viruses.

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References

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