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. 1974 Mar;71(3):962-5.
doi: 10.1073/pnas.71.3.962.

Human antigen and enzyme markers in man-Chinese hamster somatic cell hybrids: evidence for synteny between the HL-A, PGM3, ME1, and IPO-B loci

H van Someren, A Westerveld, A Hagemeijer, J R Mees, P Meera Khan, O B Zaalberg

Human antigen and enzyme markers in man-Chinese hamster somatic cell hybrids: evidence for synteny between the HL-A, PGM3, ME1, and IPO-B loci

H van Someren et al. Proc Natl Acad Sci U S A. 1974 Mar.

Abstract

In man-Chinese hamster somatic cell hybrids the segregation of the loci for 27 human enzyme markers and the species-specific surface antigens, including the HL-A histocompatibility antigens, was studied. The results show a synteny of the human loci for phosphoglucomutase 3, cytoplasmic malic enzyme, tetrameric indophenol oxidase, and HL-A. Furthermore, evidence is presented that the loci for the human species-specific antigens are distributed over several chromosomes.

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