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Clinical Trial
. 1973 Mar;3(3):332-4.
doi: 10.1128/AAC.3.3.332.

Trial of the antiviral action of isoprinosine against rhinovirus infection of volunteers

A J Soto, T S Hall, S E Reed
Clinical Trial

Trial of the antiviral action of isoprinosine against rhinovirus infection of volunteers

A J Soto et al. Antimicrob Agents Chemother. 1973 Mar.

Abstract

Isoprinosine (NPT-10381) was given orally to a group of 22 volunteers at a daily dose of 6 g for 7 days; a control group of 23 volunteers received placebo. Volunteers were inoculated intranasally with both rhinovirus type 9 and rhinovirus type 31, and the clinical picture, extent of virus shedding, and serological responses were assessed. There was no evidence that the compound had useful antiviral activity under the conditions of this trial.

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References

    1. Arch Gesamte Virusforsch. 1968;23(3):236-44 - PubMed
    1. Antimicrob Agents Chemother. 1972 Sep;2(3):224-8 - PubMed
    1. Am Rev Respir Dis. 1963 Sep;88:SUPPL 128-34 - PubMed

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