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. 1974 May;27(5):901-5.
doi: 10.1128/am.27.5.901-905.1974.

The plaque-antiserum method: an assay of virus infectivity and an experimental model of virus infection

The plaque-antiserum method: an assay of virus infectivity and an experimental model of virus infection

S De Flora. Appl Microbiol. 1974 May.

Abstract

Areas of cytopathic effect can be circumscribed in cell monolayers by adding antiserum to the liquid nutrient medium after adsorption of virus. This procedure represents a simple and reliable tool for the titration of virus infectivity and provides an experimental model for studying some aspects of virus infection.

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