The plaque-antiserum method: an assay of virus infectivity and an experimental model of virus infection
- PMID: 4364462
- PMCID: PMC380174
- DOI: 10.1128/am.27.5.901-905.1974
The plaque-antiserum method: an assay of virus infectivity and an experimental model of virus infection
Abstract
Areas of cytopathic effect can be circumscribed in cell monolayers by adding antiserum to the liquid nutrient medium after adsorption of virus. This procedure represents a simple and reliable tool for the titration of virus infectivity and provides an experimental model for studying some aspects of virus infection.
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