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. 1974 Jul;10(1):123-7.
doi: 10.1128/iai.10.1.123-127.1974.

Oxygen uptake by Treponema pallidum

C D Cox, M K Barber

Oxygen uptake by Treponema pallidum

C D Cox et al. Infect Immun. 1974 Jul.

Abstract

Virulent Treponema pallidum has been shown to consume O(2) at a rate similar to that of the known aerobic spirochaete, Leptospira. Such O(2) uptake is cyanide sensitive, indicating a functioning cytochrome oxidase. Inhibition of O(2) uptake by azide, chlorpromazine, and amytal further suggests a functioning electron transport system for the oxidation of nicotinamide adenine dinucleotide (reduced) to O(2). Evidence is consistent with the probability that this terminal electron-transport system is coupled to oxidative phosphorylation. The potential significance of these findings is discussed.

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