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. 1974 Sep;14(3):517-21.
doi: 10.1128/JVI.14.3.517-521.1974.

Inhibition of a vesicular stomatitis virus mutant by rifampin

M C Moreau

Inhibition of a vesicular stomatitis virus mutant by rifampin

M C Moreau. J Virol. 1974 Sep.

Abstract

Rifampin reversibly inhibits the intracellular replication of a VSV mutant, whereas a revertant variant selected from this viral population, as well as the wild strain, are not affected by this drug. Rifampin inhibits transcriptase activity of the sensitive mutant only and, consequently, total viral RNA synthesis decreases significantly in the cells.

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References

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    1. J Antibiot (Tokyo). 1968 Mar;21(3):234-6 - PubMed
    1. Nature. 1969 Apr 19;222(5190):273-4 - PubMed
    1. Nature. 1969 Apr 26;222(5191):341-5 - PubMed
    1. Proc Natl Acad Sci U S A. 1970 Jun;66(2):572-6 - PubMed

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