Brominated benzene induction of hepatic porphyria
- PMID: 437040
- DOI: 10.1007/BF01922739
Brominated benzene induction of hepatic porphyria
Abstract
Unlike the highly porphyrinogenic fungicide hexachlorobenzene, hexabromobenzene was a poor inducer of porphyria. Similarly, 1,2-dibromobenzene and 1,2,4-tribromobenzene, while causing small increases in hepatic porphyrins, did not increase ALA synthetase or the urinary excretion of porphobilinogen (PBG), aminolevulinic acid (ALA) or porphyrins.
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