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. 1974 Sep;10(3):471-4.
doi: 10.1128/iai.10.3.471-474.1974.

Recurrent cutaneous herpes simplex in hairless mice

G E Underwood, S D Weed

Recurrent cutaneous herpes simplex in hairless mice

G E Underwood et al. Infect Immun. 1974 Sep.

Abstract

Passively immunized hairless mice were inoculated cutaneously with herpes simplex virus. Thirty-nine days later, when the primary cutaneous lesions had completely healed, the mice were treated subcutaneously with prednisone. Within 12 to 30 days after starting prednisone treatment, herpesvirus was recovered by skin swabs from 12 of 71 (17%) of the treated mice. This new model has potential application for understanding and treating recurrent cutaneous herpes infections.

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References

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