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. 1974 Sep;71(9):3372-6.
doi: 10.1073/pnas.71.9.3372.

Biological activity of a growth factor for ovarian cells

K L Jones, D Gospodarowicz

Biological activity of a growth factor for ovarian cells

K L Jones et al. Proc Natl Acad Sci U S A. 1974 Sep.

Abstract

The biological activity of a protein growth factor is described. This factor was isolated from bovine pituitary tissue, and its activity was tested on cells of rat ovarian origin. Activity was assayed as growth-promoting potential measured by cell counts and is concentrationdependent. Similar growth stimulation was not produced by several cyclic nucleotides tested, neither was there crossreactivity between this growth factor and a chemically similar one produced by rat liver cells.

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