Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1974 May;140(2):175-83.
doi: 10.1042/bj1400175.

The uptake and metabolism of (32-P)pyrophosphate by mouse calvaria in vitro

A Jung, S Bisaz, U Gebauer, R G Russell, D B Morgan, H Fleisch

The uptake and metabolism of (32-P)pyrophosphate by mouse calvaria in vitro

A Jung et al. Biochem J. 1974 May.

Abstract

In order to study the uptake and metabolism of PP(i) by bone, (32)PP(i) was added to the medium surrounding explanted mouse calvaria maintained in organ culture. Most of the PP(i) was hydrolysed during incubation, but there was a measurable entry of intact PP(i) into bone. When (32)P(i) was added to the medium, synthesis of PP(i) and organic phosphates from P(i) was observed in bone. There was no detectable passage of PP(i) from bone into the medium. These results are discussed in terms of two models of pyrophosphate hydrolysis and exchange. Some quantitative estimates about the fate of PP(i) in bone were made.

PubMed Disclaimer

References

    1. Anal Biochem. 1970 Sep;37(1):32-43 - PubMed
    1. Am J Physiol. 1966 Sep;211(3):821-5 - PubMed
    1. Exp Cell Res. 1966 Jan;41(1):174-89 - PubMed
    1. Calcif Tissue Res. 1970;4(4):339-49 - PubMed
    1. Proc Soc Exp Biol Med. 1966 Jun;122(2):317-20 - PubMed