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. 1974 Nov;143(2):469-71.
doi: 10.1042/bj1430469.

Nuclear protein kinase activity in glucagon-stimulated perfused rat livers

W K Palmer, M Castagna, D A Walsh

Nuclear protein kinase activity in glucagon-stimulated perfused rat livers

W K Palmer et al. Biochem J. 1974 Nov.

Abstract

Nuclei isolated from glucagon-stimulated perfused rat livers contained 2-3 times as much protein kinase activity as did nuclei from control animals. In the presence of either the heat-stable inhibitor or the protein kinase regulatory subunit the elevated cyclic AMP-independent enzyme activity from stimulated nuclei was inhibited to an activity equivalent to that found in controls.

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