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. 1966 Oct;92(4):952-5.
doi: 10.1128/jb.92.4.952-955.1966.

Transformation of pneumococcal M protein

D S Feingold, R Austrian

Transformation of pneumococcal M protein

D S Feingold et al. J Bacteriol. 1966 Oct.

Abstract

Feingold, David S. (The University of Pennsylvania School of Medicine, Philadelphia), and Robert Austrian. Transformation of pneumococcal M protein. J. Bacteriol. 92:952-955. 1966.-Antisera prepared with vaccines of noncapsulated pneumococci of a given M protein type and absorbed with organisms of heterologous M protein type agglutinated specifically the homologous organisms. Specific anti-M protein sera can be used as selective reagents to permit isolation of organisms of heterologous M protein type from mixed populations. This capacity of anti-M protein sera was employed to facilitate recovery of intraspecific M protein transformants of pneumococcus. Attempted interspecific transfer of group A beta-hemolytic streptococcal M protein to pneumococcus by means of transformation reactions, however, was not accomplished.

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References

    1. J Exp Med. 1952 Dec;96(6):555-68 - PubMed
    1. J Exp Med. 1955 May 1;101(5):557-76 - PubMed

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