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. 1967 Nov 3;158(3801):660-2.
doi: 10.1126/science.158.3801.660.

Daily rhythm in tyrosine concentration in human plasma: persistence on low-protein diets

R J Wurtman, C Chou, C M Rose

Daily rhythm in tyrosine concentration in human plasma: persistence on low-protein diets

R J Wurtman et al. Science. .

Abstract

The concentration of tyrosine in the plasma of normal males varies diurnally. It is lowest (9.5 +/- 0.35 micrograms per milliliter) between 0130 and 0230 hours and rises to a peak of 16.2 +/- 0.82 micrograms per milliliter by 1030 hours. This rhythm persists when subjects are maintained for 2 weeks on a diet that is very low in protein.

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