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. 1970 Oct;119(4):673-5.
doi: 10.1042/bj1190673.

The stereochemistry of hydrogen transfer from reduced nicotinamide-adenine dinucleotide phosphate in the reduction of ethylenic linkages during cholesterol biosynthesis

D C Wilton, I A Watkinson, M Akhtar

The stereochemistry of hydrogen transfer from reduced nicotinamide-adenine dinucleotide phosphate in the reduction of ethylenic linkages during cholesterol biosynthesis

D C Wilton et al. Biochem J. 1970 Oct.

Abstract

It is shown that during the saturation of steroid carbon-carbon double bonds at Delta(24,25) and Delta(14,15) the ;hydride ion' originates from the 4B side of the NADPH.

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