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. 1971 Nov;68(11):2627-30.
doi: 10.1073/pnas.68.11.2627.

Abnormal autolytic enzyme in a pneumococus with altered teichoic acid composition

A Tomasz, M Westphal

Abnormal autolytic enzyme in a pneumococus with altered teichoic acid composition

A Tomasz et al. Proc Natl Acad Sci U S A. 1971 Nov.

Abstract

Pneumococci in which the choline component of the cell wall teichoic acid was replaced by ethanolamine contain an abnormal autolytic enzyme that has a low molecular weight and low activity in contrast to the enzyme typical of choline-containing bacteria that has a high molecular weight and high activity. The abnormal autolysin can be converted to the normal (cholinetype) enzyme by incubation in vitro with choline-containing cell walls.

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