Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1971 Nov;68(11):2734-8.
doi: 10.1073/pnas.68.11.2734.

Appearance of T-cell markers in bone marrow rosette-forming cells after incubation with thymosin, a thymic hormone

J F Bach, M Dardenne, A L Goldstein, A Guha, A White

Appearance of T-cell markers in bone marrow rosette-forming cells after incubation with thymosin, a thymic hormone

J F Bach et al. Proc Natl Acad Sci U S A. 1971 Nov.

Abstract

After incubation with thymosin, a thymic hormone, normal bone marrow rosette-forming cells acquire T-cell characteristics, including increased sensitivity to azathioprine, anti-lymphocyte serum, and anti-theta serum. This activity of thymosin provides a new sensitive and reproducible bioassay for thymosin, and is well correlated with an in vivo graft-versus-host assay. In addition, incubation of spleen cells from adult thymectomized mice with thymosin in vitro restores to normal their diminished sensitivity to azathioprine and anti-lymphocte serum.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1966 Sep;56(3):1010-7 - PubMed
    1. Nature. 1968 Feb 17;217(5129):658-9 - PubMed
    1. Nature. 1968 Sep 28;219(5161):1391-2 - PubMed
    1. Proc Natl Acad Sci U S A. 1968 Nov;61(3):875-82 - PubMed
    1. Nature. 1969 Jun 7;222(5197):998-9 - PubMed

MeSH terms

LinkOut - more resources