The effect of penicillamine on radiation-induced pulmonary lethality in mice
- PMID: 441391
- DOI: 10.1148/131.3.791
The effect of penicillamine on radiation-induced pulmonary lethality in mice
Abstract
The collagen inhibitor D-penicillamine was evaluated as a potential radiation reaction preventive agent by studying its effect on deaths attributed to pulmonary damage in mice. Long-term administration of D-penicillamine at a rate of 100 mg/kg/day had no significant effect on the LD50/160 in mice following pulmonary irradiation.
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