Studies on thymus products. 3. Epithelial origin of the serum thymic factor
- PMID: 4421188
- PMCID: PMC1445565
Item in Clipboard
Studies on thymus products. 3. Epithelial origin of the serum thymic factor
Immunology.
1974 Aug.
Abstract
Serum thymic factor (TF) has been tested by its action on spleen rosette-forming cells from adult thymectomized mice. It has been confirmed in a blind study using coded serum samples that TF disappeared early after adult thymectomy and reappeared after grafting a thymus, either as a free graft or enclosed in cell impermeable diffusion chambers. Similar reconstitution was also obtained by grafting a non-lymphoid epithelial thymoma or pure epithelial thymus, obtained by in vivo incubation of a thymus within a diffusion chamber in an intermediate host. Conversely, TF levels were not restored in thymectomized animals treated with dispersed spleen cells or with dispersed thymic lymphocytes.
Similar articles
-
Studies on thymus products. VII. Presence of thymic hormone in urodele serum.Ann Immunol (Paris). 1973 Nov;124(4):465-9. Ann Immunol (Paris). 1973. PMID: 4599569 No abstract available.
-
Studies on thymus products. II. Demonstration and characterization of a circulating thymic hormone.Immunology. 1973 Sep;25(3):353-66. Immunology. 1973. PMID: 4542646 Free PMC article.
-
Thymus dependency of rosette-forming cells: evidence for a circulating thymic hormone.Transplant Proc. 1972 Sep;4(3):345-50. Transplant Proc. 1972. PMID: 4562763 No abstract available.
-
The role of the thymus and thymic humoral factors in immunotherapy of aplastic and proliferative diseases of the hemopoietic system.Acta Med Pol. 1976;17(1):1-17. Acta Med Pol. 1976. PMID: 769487 Review. No abstract available.
-
[Thymus hormones and immunity].Usp Sovrem Biol. 1977 Jan-Feb;83(1):97-111. Usp Sovrem Biol. 1977. PMID: 331727 Review. Russian. No abstract available.
Cited by
-
Morphological restoration of gonadotrope population by thymulin gene therapy in nude mice.Histol Histopathol. 2009 Jun;24(6):729-35. doi: 10.14670/HH-24.729. Histol Histopathol. 2009. PMID: 19337971 Free PMC article.
-
Identification of thymostimulin secreting cells in calf thymus by immunoperoxidase method.Histochemistry. 1984;80(3):207-11. doi: 10.1007/BF00495767. Histochemistry. 1984. PMID: 6373680
-
Class II major histocompatibility complex molecules regulate the development of the T4+T8- inducer phenotype of cultured human thymocytes.Proc Natl Acad Sci U S A. 1985 Dec;82(23):8178-82. doi: 10.1073/pnas.82.23.8178. Proc Natl Acad Sci U S A. 1985. PMID: 2933749 Free PMC article.
-
Characterization of facteur thymique sérique (FTS) in the thymus. I. Fixation of anti-FTS antibodies on thymic reticulo-epithelial cells.Clin Exp Immunol. 1980 Dec;42(3):470-6. Clin Exp Immunol. 1980. PMID: 7011612 Free PMC article.
-
Amplification of the proliferative response to alloantigen by a factor present in an extract of syngeneic thymic lymphoid cells.Proc Natl Acad Sci U S A. 1978 Sep;75(9):4474-8. doi: 10.1073/pnas.75.9.4474. Proc Natl Acad Sci U S A. 1978. PMID: 279929 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous