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. 1974 Nov 30;4(5943):494-6.
doi: 10.1136/bmj.4.5943.494.

Cell-mediated immunity to intrinsic factor in autoimmune disorders

D James, G Asherson, I Chanarin, N Coghill, S Hamilton, R L Himsworth, D Webster

Cell-mediated immunity to intrinsic factor in autoimmune disorders

D James et al. Br Med J. .

Abstract

Evidence of cell-mediated immunity to gastric intrinsic factor was present in 86% of patients with pernicious anaemia and in at least 13% of patients with hyperthyroidism, 21% of patients with atrophic gastritis, and four out of nine (46%) patients with hypogammaglobulinaemia. Controls gave negative results. The four patients with hypogammaglobulinaemia and cell-mediated immunity to intrinsic factor had evidence of impaired gastric function.

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References

    1. J Biol Chem. 1967 Mar 10;242(5):1004-9 - PubMed
    1. Clin Exp Immunol. 1970 Feb;6(2):181-7 - PubMed
    1. Ann Intern Med. 1970 Apr;72(4):499-504 - PubMed
    1. Am J Med. 1970 Jun;48(6):787-91 - PubMed
    1. Lancet. 1970 Jul 4;2(7662):9-12 - PubMed

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