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. 1974 Oct;27(4):723-7.

'Weak A' phenotypes. Relationship between red cell agglutinability and antigen site density

J P Cartron, A Gerbal, N C Hughes-Jones, C Salmon

'Weak A' phenotypes. Relationship between red cell agglutinability and antigen site density

J P Cartron et al. Immunology. 1974 Oct.

Abstract

Thirty-five weak A samples including fourteen A3, eight Ax, seven Aend, three Am and three Ae1 were studied in order to determine their A antigen site density, using an IgG anti-A labelled with 125I. The values obtained ranged between 30,000 A antigen sites for A3 individuals, and 700 sites for the Ae1 red cells.

The hierarchy of values observed made it possible to establish a quantitative relationship between the red cell agglutinability of these phenotypes measured under standard conditions, and their antigen site density.

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