Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1974 Apr;50(4):603-5.
doi: 10.1111/j.1476-5381.1974.tb08596.x.

Some shortcomings of direct intraventricular injection in mice

G G Shaw

Some shortcomings of direct intraventricular injection in mice

G G Shaw. Br J Pharmacol. 1974 Apr.

Abstract

The use of X-ray photography following injection of iophendylate to verify that intraventricular injections in mice have been satisfactorily accomplished is misleading since it fails to detect leakage into the periphery. Radioactive labelling reveals that a substantial proportion of the injected material is rapidly carried to the periphery in the bloodstream.

PubMed Disclaimer

References

    1. J Pharm Pharmacol. 1966 Sep;18(9):621-3 - PubMed
    1. J Physiol. 1967 Oct;192(3):805-13 - PubMed
    1. Br J Pharmacol. 1971 Jun;42(2):205-14 - PubMed
    1. Nature. 1950 Nov 25;166(4230):910-1 - PubMed
    1. Br J Pharmacol Chemother. 1957 Mar;12(1):12-5 - PubMed

LinkOut - more resources