In vitro inhibition of Coccidioides immitis strains with amphotericin B plus rifampin
- PMID: 4451350
- PMCID: PMC444736
- DOI: 10.1128/AAC.6.6.783
In vitro inhibition of Coccidioides immitis strains with amphotericin B plus rifampin
Abstract
Rifampin was shown in vitro to decrease the amphotericin B minimal inhibitory concentrations of all of 10 strains of Coccidioides immitis tested. These decreases ranged from two- to fourfold and occurred with rifampin concentrations of 10 to 40 mug/ml. Rifampin alone was without effect.
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