[Hypervitaminosis A and the state of the chromosome apparatus of the rat bone marrow cells]
- PMID: 446710
[Hypervitaminosis A and the state of the chromosome apparatus of the rat bone marrow cells]
Abstract
In experiments on rats overdoses of vitamin A produced an increased frequency of cells with chromosomal aberrations and elevated number of polyploid cells. Still more pronounced disturbances were recorded in the structure and ploidity of chromosomes if hypervitaminosis A was accompanied by deficient protein nutrition.