Zinc protoporphyrin in the erythrocytes of patients with lead intoxication and iron deficiency anemia
- PMID: 4469690
- DOI: 10.1126/science.186.4167.936
Zinc protoporphyrin in the erythrocytes of patients with lead intoxication and iron deficiency anemia
Abstract
The fluorescent porphyrin in the erythrocytes of patients with lead intoxication or with iron deficiency anemia is zinc protoporphyrin that is bound to globin moieties, probably at heme binding sites.
Similar articles
-
Erythropoietic protoporphyria and lead intoxication: the molecular basis for difference in cutaneous photosensitivity. II. Different binding of erythrocyte protoporphyrin to hemoglobin.J Clin Invest. 1975 Dec;56(6):1528-35. doi: 10.1172/JCI108234. J Clin Invest. 1975. PMID: 1202083 Free PMC article.
-
Free erythrocyte protoporphyrin (FEP) and zinc protoporphyrin (ZnP) as biological parameters for lead poisoning.Int Arch Occup Environ Health. 1984;53(4):365-77. doi: 10.1007/BF00380676. Int Arch Occup Environ Health. 1984. PMID: 6715060
-
Erythrocyte delta-aminolaevulinic acid dehydratase activity and blood protoporphyrin concentrations as indices of lead exposure and altered haem biosynthesis.Clin Sci (Lond). 1979 Jan;56(1):61-9. doi: 10.1042/cs0560061. Clin Sci (Lond). 1979. PMID: 477184 No abstract available.
-
[Zinc-containing protoporphyrin and hemoglobin].Vutr Boles. 1987;26(2):7-12. Vutr Boles. 1987. PMID: 3300036 Review. Bulgarian. No abstract available.
-
Interaction of iron deficiency and lead and the hematologic findings in children with severe lead poisoning.Pediatrics. 1988 Feb;81(2):247-54. Pediatrics. 1988. PMID: 3277157 Review.
Cited by
-
Vanadium induced impairment of haem synthesis.Br J Ind Med. 1989 Oct;46(10):744-7. doi: 10.1136/oem.46.10.744. Br J Ind Med. 1989. PMID: 2818962 Free PMC article.
-
Metal ion selectivity and substrate inhibition in the metal ion chelation catalyzed by human ferrochelatase.J Biol Chem. 2009 Dec 4;284(49):33795-9. doi: 10.1074/jbc.M109.030205. Epub 2009 Sep 19. J Biol Chem. 2009. PMID: 19767646 Free PMC article.
-
The porphyrin center as a regulator for metal-ligand covalency and π hybridization in the entire molecule.Phys Chem Chem Phys. 2021 Nov 10;23(43):24765-24772. doi: 10.1039/d1cp03944j. Phys Chem Chem Phys. 2021. PMID: 34714305 Free PMC article.
-
Differential effects of metalloporphyrins on messenger RNA levels of delta-aminolevulinate synthase and heme oxygenase. Studies in cultured chick embryo liver cells.J Clin Invest. 1994 Aug;94(2):649-54. doi: 10.1172/JCI117381. J Clin Invest. 1994. PMID: 8040318 Free PMC article.
-
Occupational lead exposure in Denmark: screening with the haematofluorometer.Br J Ind Med. 1979 Feb;36(1):52-8. doi: 10.1136/oem.36.1.52. Br J Ind Med. 1979. PMID: 444441 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources