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. 1974 Dec 21;4(5946):695-6.
doi: 10.1136/bmj.4.5946.695.

Neonatal hyperthyroidism and long-acting thyroid stimulator protector

J Nutt, F Clark, R G Welch, R Hall

Neonatal hyperthyroidism and long-acting thyroid stimulator protector

J Nutt et al. Br Med J. .

Abstract

Neonatal hyperthyroidism has been thought to result from transplacental passage of long-acting thyroid stimulator (L.A.T.S.) from a mother with Graves's disease. A case is presented here in which no L.A.T.S. was detected in the mother or neonate but another immunoglobulin, L.A.T.S. protector, a specific human thyroid stimulator, was shown to be present in the mother's serum. This stimulator may have been the cause of the neonatal hyperthyroidism.

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