Cell separation on affinity columns: the isolation of immunospecific precursor cells from unimmunized mice (lactoside hapten-lymphocyte receptors-immunology)
- PMID: 4500553
- PMCID: PMC427538
- DOI: 10.1073/pnas.69.1.34
Cell separation on affinity columns: the isolation of immunospecific precursor cells from unimmunized mice (lactoside hapten-lymphocyte receptors-immunology)
Abstract
We have used affinity columns to isolate from the spleens of unimmunized mice a population of lymphocytes that specifically bind a lactoside hapten. These cells are able to initiate an antibody response to azophenyl-beta-lactoside when transferred to appropriate irradiated recipients.
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