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. 1972 Jun;69(6):1455-9.
doi: 10.1073/pnas.69.6.1455.

Environmental stimuli in the progression of BHK-21 cells through the cell cycle

M Shodell

Environmental stimuli in the progression of BHK-21 cells through the cell cycle

M Shodell. Proc Natl Acad Sci U S A. 1972 Jun.

Abstract

An L-cell line adapted to grow in protein-free medium is a source of material that stimulates the proliferation of serum-dependent BHK cells under otherwise protein-free conditions. The material produced by the L-cells is resolvable into separate DNA-synthetic and mitotic stimulatory activities. The stimulation of mitosis is dependent upon the presence of one or more heat-labile macromolecules, which can be concentrated by ultrafiltration, and at least one dialyzable component is essential for the initiation of DNA synthesis.

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References

    1. Proc Soc Exp Biol Med. 1960 Apr;103:688-91 - PubMed
    1. J Cell Biol. 1966 Sep;30(3):539-53 - PubMed
    1. Exp Cell Res. 1967 Nov;48(2):283-99 - PubMed
    1. Nature. 1970 Dec 19;228(5277):1186-7 - PubMed
    1. J Cell Physiol. 1971 Apr;77(2):121-34 - PubMed

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