The effects of stimulant medication on the growth of hyperkinetic children
- PMID: 450520
The effects of stimulant medication on the growth of hyperkinetic children
Abstract
This article reviews the literature on possible growth-suppressing effects of stimulant medications in the long-term treatment of children with the hyperkinetic behavior syndrome. The evidence clearly indicates a temporary retardation in the rate of growth in weight and suggests a temporary slowing of growth in stature, but no effect on adult stature or weight. This temporary effect on growth is present during the first few years of treatment and seems related to drug dosage and to the presence or absence of drug holidays. These conclusions related specifically to treatment during the prepubertal period; little is known of the growth-related effects of treatment extending through pubescence.
Similar articles
-
Factors influencing the suppressant effects of two stimulant drugs on the growth of hyperactive children.Pediatrics. 1973 Apr;51(4):660-7. Pediatrics. 1973. PMID: 4697515 No abstract available.
-
Growth disturbances in hyperkinetic children.Pediatrics. 1980 Jul;66(1):152-4. Pediatrics. 1980. PMID: 7402783 No abstract available.
-
Depression of growth in hyperactive children on stimulant drugs.N Engl J Med. 1972 Aug 3;287(5):217-20. doi: 10.1056/NEJM197208032870503. N Engl J Med. 1972. PMID: 4556640 Clinical Trial. No abstract available.
-
The growth of children given stimulant drugs.Nutr Rev. 1973 Mar;31(3):91-2. doi: 10.1111/j.1753-4887.1973.tb05999.x. Nutr Rev. 1973. PMID: 4574834 Review. No abstract available.
-
[Stimulants in the treatment of hyperkinetic behavior disorders].Harefuah. 1971 Mar 15;80(6):298-302. Harefuah. 1971. PMID: 4946564 Review. Hebrew. No abstract available.
Cited by
-
Hyperactivity: nature of the syndrome and its natural history.J Autism Dev Disord. 1984 Mar;14(1):39-56. doi: 10.1007/BF02408554. J Autism Dev Disord. 1984. PMID: 6368521
-
Adverse reactions in children. Special considerations in prevention and management.Drug Saf. 1991 May-Jun;6(3):171-82. doi: 10.2165/00002018-199106030-00003. Drug Saf. 1991. PMID: 2064761 Review.
-
Effect of Chronic Methylphenidate Treatment in a Female Experimental Model of Parkinsonism.Neurotox Res. 2021 Jun;39(3):667-676. doi: 10.1007/s12640-021-00347-9. Epub 2021 Mar 5. Neurotox Res. 2021. PMID: 33666887
-
Risks and benefits of drugs used in the management of the hyperactive child.Drug Saf. 1993 Jul;9(1):38-50. doi: 10.2165/00002018-199309010-00004. Drug Saf. 1993. PMID: 8347290 Review.
-
Methylphenidate exposure induces dopamine neuron loss and activation of microglia in the basal ganglia of mice.PLoS One. 2012;7(3):e33693. doi: 10.1371/journal.pone.0033693. Epub 2012 Mar 21. PLoS One. 2012. PMID: 22470460 Free PMC article.