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. 1972 Oct;69(10):2840-1.
doi: 10.1073/pnas.69.10.2840.

A unifying hypothesis concerning the nature of malignant growth

R W Holley

A unifying hypothesis concerning the nature of malignant growth

R W Holley. Proc Natl Acad Sci U S A. 1972 Oct.

Abstract

It is suggested that the crucial change in a malignant cell is an alteration in the cell surface membrane that results in increased internal concentrations of nutrients that regulate cell growth.

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References

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    1. Proc Natl Acad Sci U S A. 1969 Nov;64(3):1049-56 - PubMed
    1. J Biol Chem. 1970 Feb 25;245(4):714-7 - PubMed

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