Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1972 Nov;69(11):3385-8.
doi: 10.1073/pnas.69.11.3385.

Synthesis of proteochondroitin sulfate by normal, nanomelic, and 5-bromodeoxyuridine-treated chondrocytes in cell culture

M J Palmoski, P F Goetinck

Synthesis of proteochondroitin sulfate by normal, nanomelic, and 5-bromodeoxyuridine-treated chondrocytes in cell culture

M J Palmoski et al. Proc Natl Acad Sci U S A. 1972 Nov.

Abstract

Chondrocytes grown in cell culture from micromelic chick sterna and 5-bromodeoxyuridine-treated normal cells showed reduced incorporation of sulfate into hyaluronidase-sensitive material as compared to normal chondrocytes. Proteochondroitin sulfate synthesized by normal embryonic chick chondrocytes in cell culture was heterogeneous on chromatography. The major chromatographic component was specifically inhibited in normal chondrocytes treated with 5-bromodeoxyuridine, and this component was absent in nanomelic chondrocytes.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1966 Jan;55(1):66-73 - PubMed
    1. Proc Natl Acad Sci U S A. 1968 Apr;59(4):1144-51 - PubMed
    1. J Biol Chem. 1969 Jan 10;244(1):77-87 - PubMed
    1. Biochem J. 1969 Aug;113(5):885-94 - PubMed
    1. Biochem J. 1969 Oct;114(4):871-6 - PubMed

MeSH terms

LinkOut - more resources