Location of ribosomal DNA in the human chromosome complement
- PMID: 4508329
- PMCID: PMC389778
- DOI: 10.1073/pnas.69.11.3394
Location of ribosomal DNA in the human chromosome complement
Abstract
Hybridization of (3)H-labeled ribosomal RNA to human chromosomes on slides resulted in specific labeling of the satellite regions of chromosomes 13, 14, 15, 21, and 22, with an over-all efficiency of about 5%. Differences between D and G chromosomes, and between associated and unassociated satellites, were not significant. Labeling of all other parts of the preparations was nonspecific, and increased in the order: extrachromosomal regions < chromosome arms < centric regions.
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