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. 1973 May;70(5):1401-5.
doi: 10.1073/pnas.70.5.1401.

The reaction of N-iodosuccinimide with the goitrogens: a model for the active iodine of the thyroid gland

L Jirousek, M Soodak

The reaction of N-iodosuccinimide with the goitrogens: a model for the active iodine of the thyroid gland

L Jirousek et al. Proc Natl Acad Sci U S A. 1973 May.

Abstract

The reactivities of N-iodosuccinimide and iodine with various goitrogenic compounds were studied with dimethylsulfoxide through which nitrogen had been bubbled as a solvent. Although iodine does not react with all of the compounds, N-iodosuccinimide does react with all of them. N-Iodosuccinimide may, therefore, serve as an interesting model for the "active iodine" of the thyroid.

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