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. 1973 Mar;70(3):747-9.
doi: 10.1073/pnas.70.3.747.

Protective effect of ascorbic acid on hepatotoxicity caused by sodium nitrite plus aminopyrine

J J Kamm, T Dashman, A H Conney, J J Burns

Protective effect of ascorbic acid on hepatotoxicity caused by sodium nitrite plus aminopyrine

J J Kamm et al. Proc Natl Acad Sci U S A. 1973 Mar.

Abstract

The oral treatment of rats with sodium ascorbate in combination with sodium nitrite and aminopyrine prevents the rise in serum alanine aminotransferase (EC 2.6.1.2) observed when nitrite and aminopyrine are given alone. Ascorbic acid also affords protection, whereas dehydroascorbic acid exerts no protective effect.

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References

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