Mitochondrial membrane potential: evidence from studies with a fluorescent probe
- PMID: 4521825
- PMCID: PMC388052
- DOI: 10.1073/pnas.71.2.583
Mitochondrial membrane potential: evidence from studies with a fluorescent probe
Abstract
The fluorescence of the probe 3,3'-dihexyl-2,2'-oxacarbocyanine (CC(6)) has been found to indicate potential across cell membranes. Results obtained in the present study using CC(6) and Drosophila mitochondria are in agreement with membrane potentials previously measured by Tupper and Tedeschi using microelectrodes. The results of both studies with Drosophila suggest that the potential across the mitochondrial membrane does not play a significant role in oxidative phosphorylation.
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