Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1974 Apr;71(4):1108-12.
doi: 10.1073/pnas.71.4.1108.

Interspersion of repetitive and single-copy sequences in nuclear ribonucleic acid of high molecular weight

D S Holmes, J Bonner

Interspersion of repetitive and single-copy sequences in nuclear ribonucleic acid of high molecular weight

D S Holmes et al. Proc Natl Acad Sci U S A. 1974 Apr.

Abstract

Nuclear RNA of high molecular weight, approximately 15 to 30 x 10(3) nucleotides long, isolated from rat ascites cells, has been shown previously to contain both middle repetitive and single-copy sequences. However, it was not known whether these sequences were located on separate molecules or whether they were interspersed within the same molecule. The present communication distinguishes between these possibilities and shows that a large proportion of nuclear RNA of high molecular weight consists of interspersed middle repetitive and single-copy sequences.

PubMed Disclaimer

References

    1. J Mol Biol. 1968 Feb 14;31(3):349-70 - PubMed
    1. Science. 1969 Jul 25;165(3891):349-57 - PubMed
    1. J Mol Biol. 1969 Feb 14;39(3):545-50 - PubMed
    1. Proc Natl Acad Sci U S A. 1971 Jan;68(1):172-6 - PubMed
    1. Nat New Biol. 1971 May 5;231(18):8-12 - PubMed

LinkOut - more resources